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Designing proteins with language models

delete2024-02-15
delete8
PRE
AI
J
Jeffrey A. Ruffolo
A
Ali Madani *
DOI：10.1038/s41587-024-02123-4delete
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Abstract

Abstract

En 中文
Protein language models learn from diverse sequences spanning the evolutionary tree and have proven to be powerful tools for sequence design, variant effect prediction and structure prediction. What are the foundations of protein language models, and how are they applied in protein engineering?

Journal

Nature Biotechnology cover
Nature Biotechnology
IF:
41.7
Papers:
1.2W
Citations:
10.1W

Organization

No organization information available