Dietary branched-chain amino acids modify the cardiac growth response to exercise in male mice

Kyle L. Fulghum

doi:10.1016/j.yjmcc.2026.06.003

Dietary branched-chain amino acids modify the cardiac growth response to exercise in male mice

2026-06-05

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Kyle L. Fulghum

H

Helen E. Collins

B

Bradford G. Hill *

DOI：10.1016/j.yjmcc.2026.06.003

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• Acute exercise transiently increases circulating BCAAs in mice. • Dietary BCAA availability modifies exercise-induced cardiac growth in male mice. • Female mice improve exercise capacity without detectable cardiac growth. • In either sex, cardiac growth is not required for improved exercise capacity.

Dietary branched-chain amino acids modify the cardiac growth response to exercise in male mice

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