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Diffusing the Blind Spot: Uterine MRI Synthesis with DiffusionModels

delete2026-01-01
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PRE
AI
J
Johanna P. Müller
A
Anika Knupfer
B
Bloess, Pedro
E
Edoardo Berardi Vittur
B
Bernhard Kainz
J
Jana Hutter
DOI:10.1007/978-3-032-05825-6_9delete
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Abstract

Abstract

En 中文
espite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient privacy concerns are critical. To overcome these barriers, we introduce a novel diffusion-based framework for uterine MRI synthesis, integrating both unconditional and conditioned Denoising Diffusion Probabilistic Models (DDPMs) and Latent Diffusion Models (LDMs) in 2D and 3D.Our approach generates anatomically coherent, high-fidelity synthetic images that closely mimic real scans and provide valuable resources for training robust diagnostic models. We evaluate generative quality using advanced perceptual and distributional metrics, benchmarking against standard reconstruction methods, and demonstrate substantial gains in diagnostic accuracy on a key classification task. A blinded expert evaluation further validates the clinical realism of our synthetic images.We release our models with privacy safeguards and a comprehensive synthetic uterine MRI dataset to support reproducible research and advance equitable AI in gynaecology. The code and data are available at:https://github.com/ividja/SynthUterus.
Keywords:
Uterus
Diffusion Models
ImageGeneration
MRI

Journal

S
SKIN IMAGE ANALYSIS, AND COMPUTER-AIDED PELVIC IMAGING FOR FEMALE HEALTH, ISIC 2025, CAPI 2025
IF:
0
Papers:
13
Citations:
0

Organization

U
university of erlangen nuremberg
Scholars:
2.8K
Papers: 1.2K
Citations: 0