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Direct current electric field suppresses NPFFR2 expression in macrophages and alters its predicted conformational dynamics

delete2025-12-03
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PRE
AI
Z
Zhuo Zuo
王亚星 cover
王亚星 (Ya Xing Wang)
M
Mengya Zhao
Y
Yanwei Fang
Y
Yunfei Chen
Z
Ziyi Zuo
Y
Yulong Sun *
DOI：10.1016/j.bbrc.2025.153094delete
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Abstract

Abstract

En 中文
• A device was developed using load cells for dcEF stimulation. • dcEF stimulation altered morphology in wildtype and Npffr2 knockout BMDMs. • NPFFR2 protein expression decreased in both wildtype and Npffr2 knockout BMDMs. • Cytoskeletal rearrangement of NPFFR2 occurred; β-actin remained unchanged. • Intensity-dependent structural changes in NPFFR2 protein were induced by dcEF.

Journal

Biochemical and Biophysical Research Communications cover
Biochemical and Biophysical Research Communications
IF:
2.2
Papers:
2.4K
Citations:
8.1W

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