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Directed Evolution of a Thermostable Laccase from Geobacillus stearothermophilus for Efficient Reduction of Oxygen

delete2026-04-14
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PRE
AI
B
Bipasa Dey
C
Cini M. Suresh
S
Shilpi Singh
T
Tarak Karmakar
P
Pravin Popinand Ingole *
T
Tanmay Dutta *
DOI：10.1016/j.biochi.2026.04.005delete
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Abstract

Abstract

En 中文
• A multicopper oxidase from G. stearothermophilus, identified as Laccase (GbsLac). • GbsLac demonstrates thermostable and thermophilic properties. • Syringaldazine biding mode reveals Met503 and Asp438 importance in catalytic site. • M503L and D438A increases the onset potential for oxygen reduction reaction.
Keywords:
Laccase
Thermostable
Directed evolution
Oxygen reduction
Catalytic site

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Biochimie cover
Biochimie
IF:
3
Papers:
5.9K
Citations:
1.2W

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I
indian institute of technology delhi
Scholars:
1.2K
Papers: 597
Citations: 0
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