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Discovery of a Handwritten Laboratory Notebook by Albert Calmette and Camille Guérin Describing Experimental Studies and Development of the BCG Vaccine for Tuberculosis
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DOI：10.1016/j.tube.2026.102767.png)
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Abstract
En 中文
The Bacille Calmette–Guérin (BCG) vaccine against tuberculosis is the most widespread vaccine in the world. Discovered by French investigators Albert Calmette and Camille Guérin at the Pasteur Institute, it remains the only effective vaccine against tuberculosis infection. This report describes the recognition and identification of a previously unknown French handwritten laboratory notebook prepared by Drs. Calmette and Camille Guérin recording their experiments performed during the development of the BCG vaccine.
Keywords:
Tuberculosis
Vaccine development
Pasteur Institute
Albert Calmette
Camile Guérin
laboratory notebook
manuscript
Bacillus Calmette–Guérin
BCG vaccine
Mycobacterium bovis
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