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Distinct Gene Expression Profiles of Ara h 2-Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy
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DOI：10.1111/all.70472.png)
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Abstract
En 中文
Peanut oral immunotherapy (OIT) is an effective way to treat peanut allergy. Patients undergoing OIT show high rates of desensitization to the triggering food items after a completed therapy. Long-term tolerance is often achieved, but the mechanism of tolerance after OIT is not well understood. In this study, we aimed to characterize the changes in allergen-specific B cell gene expression caused by peanut OIT and the effects of extended allergen avoidance after OIT.
Keywords:
B cell regulation
OIT
peanut allergy
tolerance induction
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