Divergent Biology and Outcomes of Somatic Transformations in Germ Cell Tumors

2026-06-30

Zachariah Thomas, MBBS

Andrew C Johns, MD

Michael Glover, MD

Emanuele Crupi, MD

Yago L Nieto, MD, PhD

John F Ward, MD, FACS

Jose A Karam, MD, FACS

Wayne L Hofstetter, MD

Monica Desai, MD

Seungtaek L Choi, MD

Amishi Y Shah, MD

John Lin, MD, MSHP

Mohammad Jad Moussa, MD

Cindy Y Jiang

Omar Alhalabi, MD

Matthew T Campbell, MD, MS *

DOI：10.1093/oncolo/oyag253

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Somatic-type malignancy (SM) of germ cell tumor (GCT) is rare but demonstrates aggressive behavior. Differences by primary site, time to transformation, and mutational status remains poorly characterized.

Divergent Biology and Outcomes of Somatic Transformations in Germ Cell Tumors

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