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DNA methylation-based classification of hematolymphoid neoplasms

delete2026-04-28
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OA
AI
A
Annapurna Saksena
C
Christin Siewert
R
Rust Turakulov
O
Omkar Singh
Z
Zied Abdullaev
T
Ting Zhou
J
Jeremiah Karrs
J
Joao Victor Alves De Castro
D
Deanna Riley
S
Shannon Skarshaug
V
Valerie Zgonc
L
Lana Sultanaeva
R
Ruifeng Teng
L
Liqiang Xi
R
Robert J. Kreitman
A
Andreas von Deimling
M
Martí Duran‐Ferrer
J
José I. Martı́n-Subero
E
Elı́as Campo
B
Benjamin Englert
DOI:10.1182/bloodadvances.2024015275delete
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Abstract

Abstract

En 中文
1. The study defines DNA methylation classes in over 1400 hematolymphoid neoplasms, correlating with known entities and revealing key subgroups. 2. Machine learning-based classifier, as proof-of-concept for future clinical tool, showed 97% diagnostic concordance in high-confidence cases.
Keywords:
DNA methylation
hematolymphoid
neoplasms
classification
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Journal

Blood Advances cover
Blood Advances
IF:
7.1
Papers:
6.0K
Citations:
2.3W

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