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DNAemia Thresholds to Discontinue Antivirals in Preemptive Management for Cytomegalovirus Seropositive Recipients After Kidney Transplantation

delete2026-04-17
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PRE
AI
M
Miehrig, Arthur Heinz MD
F
Foresto, Renato Demarchi MD, PhD
T
Tedesco-Silva, Helio MD, PhD
J
José Medina‐Pestana
R
Requião-Moura, Lúcio MD, PhD
DOI:10.1097/TP.0000000000005695delete
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Abstract

Abstract

En 中文
Treatment of cytomegalovirus (CMV) after kidney transplantation aims to achieve cessation of viral replication; however, the use of highly sensitive DNA assays creates uncertainty regarding the optimal DNAemia threshold for safely discontinuing antiviral therapy. We evaluated the safety and efficacy of ending antiviral therapy at a lower DNAemia cutoff (<log10 2.30; 200 IU/mL), compared with undetectable DNAemia (<log10 1.49; 31 IU/mL).

Journal

Transplantation cover
Transplantation
IF:
5
Papers:
2.8W
Citations:
2.3W

Organization

U
universidade federal de sao paulo
Scholars:
404
Papers: 156
Citations: 1
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