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Does compulsion explain addiction?

delete2024-04-08
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OA
AI
A
Andreas Heinz
S
Stefan Gutwinski
N
Nadja Samia Bahr *
R
Rainer Spanagel *
G
G. Di Chiara
DOI:10.1111/adb.13379delete
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Abstract

Abstract

En 中文
One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug-seeking behaviour and that compulsion is the maladaptive persistence of responding despite adverse consequences. Here we discuss that compulsive behaviour as defined primarily from the perspective of animal experimentation falls short of the clinical phenomena and their neurobiological correlates. Thus for the human condition, the concept of compulsive habbits should be critically addressed and potentially revised.
Keywords:
addiction
animals
compulsive behaviour
drug-seeking behaviour
habits

Journal

Addiction Biology cover
Addiction Biology
IF:
2.6
Papers:
2.4K
Citations:
4.6K

Organization

B
Berlin Institute of Health
Scholars:
3.9W
Papers: 3.0W
Citations: 6.6K
C
Charite Universitatsmedizin Berlin
Scholars:
1.6W
Papers: 1.3W
Citations: 29
H
Humboldt University of Berlin
Scholars:
3.2W
Papers: 2.7W
Citations: 47
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