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Dual immunometabolic regulation and therapeutic targeting of TAMs, microglia and astrocytes in brain metastasis of non-small cell lung cancer
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DOI:10.1016/j.bbcan.2026.189601.png)
Abstract
En 中文
• First systematic review of TAMs, microglia, and astrocytes in NSCLC brain metastasis. • Elucidates dual immunometabolic regulation by these CNS cells. • Identifies novel subpopulations beyond M1/M2, like C1Q+/SPP1+ TAMs. • Integrates emerging innovative therapeutic strategies targeting the TME.
Keywords:
TAMs
microglia
astrocytes
brain metastasis
immunometabolic regulation
Journal
B
IF:
0
Papers:
105
Citations:
0
