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Dual modal pathomics model for colorectal cancer early recurrence prediction and mutation landscape analysis
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DOI：10.1016/j.isci.2026.116459.png)
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Abstract
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• A dual-modal pathomics model predicts early recurrence in colorectal cancer • Combining H&E and Ki-67 images improves recurrence prediction • The UNI-based model performs robustly across validation cohorts • MTHFR and DPYD mutations appear enriched in the predicted high-risk group
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health sciences
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