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Dynamic Evaluation of Peripheral Hypoxia (DEPH): a method for the assessment of nocturnal hypoxic burden in respiratory diseases using pulse-oximetry
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DOI：10.1016/j.sleep.2026.109103.png)
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Abstract
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• Existing hypoxic burden methods are heterogeneous and lack standardization. • They have been validated almost exclusively in OSA on polysomnography. • DEPH is a novel signal-based HB algorithm for nocturnal oximetry. • DEPH captures the shape and variability of SpO2 dynamics adaptively. • Standardization (sHB) allows direct comparison across HB methods.
Keywords:
DEPH
Hypoxic burden
Respiratory diseases
Sleep apnea
Sleep-related hypoxemia
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