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Dynamic regulation of fibroblast heterogeneity in regeneration repair and bone diseases

delete2026-07-24
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PRE
AI
S
Shuyi Xing
J
Jun Wang
J
Jingzhen Mo
F
Feng He
P
Ping Liu
Y
Yu Zhang
Y
Yiming Wang
Y
Yang Xue *
J
Jianfei Yan *
DOI：10.1016/j.metabol.2026.156713delete
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Abstract

Abstract

En 中文
• Fibroblasts are active niche organizers, not passive ECM producers. • A three-dimensional framework (identity, niche, stage) guides fibroblast heterogeneity. • Signaling, metabolism, and communication networks control fibroblast fate. • Osteoimmune crosstalk determines regeneration versus fibrosis.

Journal

M
Metabolism-Clinical and Experimental
IF:
11.9
Papers:
9.6K
Citations:
2.1W

Organization

T
the fourth military medical university
Scholars:
1.4K
Papers: 259
Citations: 0
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