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Early decrease in circulating miR-21 correlates with preeclampsia occurrence and Outcomes: A retrospective study

delete2026-05-04
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PRE
AI
H
Hui Geng
Y
Yuan Li
Y
Yongzhen Chen
B
Bide Duan
K
Kun Dong *
DOI：10.1016/j.preghy.2026.101475delete
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Abstract

Abstract

En 中文
• Early pregnancy levels of circulating miR-21 are significantly lower in women who later develop preeclampsia. • Lower first-trimester miR-21 levels correlate with more severe disease, including higher blood pressure and proteinuria. • First-trimester miR-21 predicts adverse pregnancy outcomes better than levels at diagnosis.
Keywords:
miR-21
preeclampsia
pregnancy outcomes
first trimester
biomarker

Journal

P
Pregnancy Hypertension
IF:
0
Papers:
202
Citations:
2

Organization

No organization information available