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Early-Life Social Enrichment Induces Divergent Cognitive-Emotional Aging along with Dorsal Hippocampal VGluT1 and Glial Alterations

delete2026-05-26
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PRE
AI
X
Xiao-Xiao Ma
J
Jia-Ya Zheng
X
Xing-Duo Yao
Y
Yajie Yu
王
王晓东 (Xiaodong Wang)
Y
Yun-Ai Su
李
李继涛 (Jitao Li) *
T
Tian-Mei Si *
DOI：10.1016/j.neurobiolaging.2026.05.011delete
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Abstract

Abstract

En 中文
• Communal nesting (CN) preserves recognition memory in aged male mice. • CN leads to elevated anxiety-like behavior in aged male mice. • CN increases VGluT1 levels and reduces glial density in the dorsal hippocampus.
Keywords:
Communal nesting
Cognitive aging
Emotional behavior
Dorsal hippocampus
VGluT1

Journal

Neurobiology of Aging cover
Neurobiology of Aging
IF:
3.5
Papers:
9.3K
Citations:
2.3W

Organization

P
peking university
Scholars:
11.5W
Papers: 8.6W
Citations: 146
Z
zhejiang university
Scholars:
17.0W
Papers: 11.9W
Citations: 152
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