Effect of Mn²⁺ levels on caproic acid production during anaerobic fermentation using ethanol and butyric acid as co-substrates

Longlong Liu

doi:10.1016/j.jbiotec.2026.04.025

Effect of Mn²⁺ levels on caproic acid production during anaerobic fermentation using ethanol and butyric acid as co-substrates

2026-05-08

0

PRE

AI

L

Longlong Liu

Y

Yingmeng Shen

S

Sen Yang

X

Xiaofeng Ji

Z

Zhengang Chen

J

Jiying Zhu *

DOI：10.1016/j.jbiotec.2026.04.025

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Abstract

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• Caproic acid yield was enhanced by 31.7% when 1 mg/L Mn²⁺ was supplemented. • A supplementation level of 20.0 mg/L Mn²⁺ resulted in pronounced over-oxidation of ethanol. • The relative abundance of Desulfovibrio was positively correlated with caproic acid production.

Keywords:

Mn²⁺ supplementation

caproic acid production

anaerobic fermentation

Desulfovibrio

ethanol over-oxidation

Effect of Mn²⁺ levels on caproic acid production during anaerobic fermentation using ethanol and butyric acid as co-substrates

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