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Effects of chemogenetic regulation of CaMKⅡα positive neurons in the ventral hippocampus on working memory impairment in the hemiparkinsonian rat
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DOI：10.1016/j.neuint.2026.106190.png)
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Abstract
En 中文
• Activation of vHIP CaMKⅡα neurons ameliorated working memory impairment in PD rats • Activation of vHIP CaMKⅡα neurons increased peak of θ rhythm of the mPFC in PD rats • Activation of vHIP CaMKⅡα neurons increased DA levels in related regions in PD rats • Inhibition of vHIP CaMKⅡα neurons had opposite effect on working memory in PD rats • Activation or inhibition of vHIP CaMKⅡα neurons had no effects in sham rats
Keywords:
vHIP CaMKⅡα neurons
working memory impairment
theta rhythm
dopamine levels
chemogenetic regulation
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