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EGFR as a context-dependent modulator of endothelial inflammation: A systematic review
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DOI：10.1016/j.cyto.2026.157183.png)
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Abstract
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• EGFR may integrate signaling from cytokines, growth factors, and mechanical stress. • NF-κB, ROS, and VEGF pathways mechanistically link EGFR to inflammation. • EGFR signaling is involved in vascular inflammation and endothelial adaptation. • Vascular effects of EGFR may be protective or detrimental in a context-dependent manner. • Comparative studies are needed to define EGFR roles in vascular homeostasis.
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