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Electroacupuncture and Parecoxib Reduce Inflammatory Injury in a Primary Dysmenorrhea Rat Model: Investigating the Role of the COX-2/NF-κB/NLRP3 Pathway
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DOI：10.2147/JPR.S512243.png)
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Abstract
En 中文
Anti-inflammatory drugs relieve primary dysmenorrhea (PDM), and nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) is a potential treatment target. Electroacupuncture (EA) is an effective alternative strategy for treating PDM as it regulates the NLRP3 inflammasome. However, the exact anti-inflammatory mechanism of EA remains unclear. Therefore, this study explored the therapeutic effect of EA on PDM and determined the potential involvement of the cyclooxygenase-2 (COX-2)/nuclear factor κB (NF-κB)/NLRP3 signaling pathway.
Keywords:
anti-inflammatory treatment
cyclooxygenase-2
prostaglandin
nuclear transcription factor
nucleotide-binding oligomerization domain-like receptor 3
Journal
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2.5
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781
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