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Electron Donor–Acceptor Mediated Hydrosulfonylation of Olefins From N-Hydroxymethylphthalimide Sulfones
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DOI：10.1002/adsc.70591.png)
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Abstract
En 中文
Sulfones are widely used sulfur-VI motifs in pharmaceuticals. We report a hydrosulfonylation strategy that employs N-hydroxymethylphthalimide sulfones as versatile sulfinyl radical precursors. In the presence of tertiary amines, NHMP sulfones form electron donor–acceptor complexes that undergo light-induced single-electron transfer to generate sulfinyl radicals in the absence of a photocatalyst. The resulting radicals add efficiently to activated olefins, affording structurally diverse sulfones under mild conditions.
Keywords:
EDA complexes
hydrosulfonylation
olefins
photochemistry
sulfinyl radicals
Journal
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4
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424
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0