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Electronic Cigarette Vapor Exposure Modifies Stroke-Induced Transcriptional and Microglial Responses in a Sex-Dependent Manner.

delete2026-05-14
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PRE
AI
S
Sophie Belle Sinder
I
Indy Cabeda Diaz
S
Shahil H. Patel
J
Julia Romagnoli
H
Harry Sharma
G
Gina G. Perez
K
Kunjan R. Dave
M
Miguel A. Perez-Pinzon
H
Helen M. Bramlett
A
Ami P. Raval *
DOI:10.1016/j.neuint.2026.106185delete
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Abstract

Abstract

En 中文
• Electronic cigarette (EC) exposure alters post-stroke inflammation in adult rats. • RNA-seq reveals post-stroke sex-specific cortical transcriptomic responses. • EC exposure increases microglial activation and reduces branching complexity. • Females are highly vulnerable to EC-exacerbated post-stroke injury.
Keywords:
Electronic cigarette
Stroke
Microglial activation
Transcriptomic responses
Sex differences

Journal

Neurochemistry International cover
Neurochemistry International
IF:
4
Papers:
5.3K
Citations:
1.0W

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