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Embryonic Stem Cell-Derived Extracellular Vesicles Alleviate Ovarian Dysfunction
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DOI：10.1016/j.mad.2026.112186.png)
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Abstract
En 中文
• ESC-EVs restore estrous cyclicity and fertility in chemotherapy-induced POI mice • ESC-EVs reduce ovarian fibrosis and suppress senescence-associated phenotypes • Granulosa cell transcriptomes are reprogrammed toward folliculogenic programs • ESC-EVs mitigate ovarian dysfunction and systemic aging-related tissue damage
Keywords:
ESC-EVs
ovarian dysfunction
fertility
senescence
granulosa cells
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