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Emergence of mobile RND-type efflux pump gene cluster tmexCD-toprJ on a broad-host-range IncC plasmid in Shewanella species in a water environment

delete2026-04-17
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OA
AI
T
Trung Duc Dao
T
Taichiro Takemura
I
Ikuro Kasuga
A
Aki Hirabayashi
N
Nguyen Thi Nga
P
Pham Hong Quynh Anh
N
Nguyen Dong Tu
L
Le Thi Trang
P
Pham Duy Thai
T
Tran Huy Hoang
H
Haruka Abe
F
Futoshi Hasebe
K
Keigo Shibayama
M
Masato Suzuki *
DOI:10.1016/j.jgar.2026.04.005delete
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Abstract

Abstract

En 中文
The spread of the mobile resistance-nodulation-division (RND)-type efflux pump tmexCD-toprJ gene cluster that confers multidrug resistance (MDR), including tigecycline resistance, in gram-negative bacteria poses a global public health threat. However, the occurrence of such clinically important antimicrobial resistance genes (ARGs) in the natural environments has not yet been well investigated. In this study, we investigated MDR aquatic bacteria in Vietnam.
Keywords:
tigecycline
tmexCD-toprJ
carbapenem
blaNDM-1
Shewanella
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Journal

Journal of Global Antimicrobial Resistance cover
Journal of Global Antimicrobial Resistance
IF:
3.2
Papers:
2.8K
Citations:
5.7K

Organization

J
japan institute for health security
Scholars:
43
Papers: 13
Citations: 0
N
national institute of hygiene and epidemiology
Scholars:
23
Papers: 6
Citations: 0
N
Nagoya University
Scholars:
3.3W
Papers: 2.5W
Citations: 2.6W
N
nagasaki university
Scholars:
1.6K
Papers: 525
Citations: 1
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