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Emerging pharmacological and neuromodulation interventions for suicidal ideation and behaviour
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DOI：10.1016/j.euroneuro.2026.112888.png)
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Abstract
En 中文
• Across 34 studies, multiple trials reported SI reduction, often within days–weeks. • Neuromodulation trials primarily evaluated accelerated rTMS/TBS and MST for SI outcomes. • Controlled pharmacotherapy signals: d-cycloserine/NRX-101, amantadine, buprenorphine. • Observational studies reported heterogeneous associations (folic acid, benztropine, NOACs, cannabis). • Major gaps: suicidal outcomes, standardized measures, and durability.
Keywords:
Suicidal ideation
Suicide attempt
Neuromodulation
Transcranial magnetic stimulation
N-methyl-D-aspartate receptor antagonists
Opioid agonists
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