Emerging roles of Dehydrogenase/Reductase (DHRS) in cancer

2026-05-06

PRE

Jun Huang

Chenpeng Tang

Xue Chen

Pai Zeng

Hongde Li

罗

罗湘建 (Xiangjian Luo) *

DOI：10.1016/j.chemphyslip.2026.105590

Original

Original request for help

Save

Abstract

En 中文

• DHRS not only participates in the metabolism of lipids, steroids and retinol, but also plays a significant role in tumorigenesis and progression. • We conducted a comprehensive systematic review of DHRS members across diverse malignancies, elucidating their associations with clinical drug resistance and chemotherapy response biomarkers. • The role of DHRS has been elaborated from the aspects of metabolic reprogramming, classical signal pathways and clinical potentials.

Keywords:

DHRS

cancer

metabolic reprogramming

drug resistance

chemotherapy response

Emerging roles of Dehydrogenase/Reductase (DHRS) in cancer

Abstract

Journal

Organization

Cited Papers

Citing Papers