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Empagliflozin for the preservation of beta-cell function in women with recent gestational diabetes: A randomized placebo-controlled trial

delete2025-09-18
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S
Shamini Murugavel
R
Ravi Retnakaran
D
Denice S. Feig
B
Bernard Zinman
C
Caroline K. Kramer *
DOI:10.1111/dom.70146delete
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Abstract

Abstract

En 中文
Women with a history of gestational diabetes (GDM) frequently have progressive beta-cell dysfunction, which may result in type 2 diabetes. However, there is a paucity of clinical studies on strategies aiming to preserve beta-cell function in this patient population. This trial evaluated whether empagliflozin can preserve beta-cell function and reduce the prevalence of dysglycemia (prediabetes/diabetes) in women with recent GDM.
Keywords:
beta-cell function
gestational diabetes
pre-diabetes
SGLT-2 inhibitor
type 2 diabetes
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

D
Diabetes Obesity and Metabolism
IF:
5.7
Papers:
6.1K
Citations:
1.7W

Organization

M
Mount Sinai Hospital
Scholars:
291
Papers: 147
Citations: 1.3K
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