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Empty large liposomes reduce cartilage degeneration in osteoarthritic rats by forming a lubricative coating
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DOI：10.1016/j.joca.2025.02.774.png)
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Abstract
En 中文
To explore the mechanism of action and structural effects of MM-II, a dispersion of “empty” multilamellar large liposomes composed of dimyristoyl phosphatidylcholine (DMPC) and dipalmitoyl phosphatidylcholine (DPPC), which durably reduced pain in a phase 2b study in knee osteoarthritis (OA) patients.
Keywords:
Liposome
Lubrication
Cartilage wear
Disease-modifying osteoarthritis drug
Intra-articular
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9
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1.3W
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2.2W
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