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Enabling rapid parallel SERS detection with integrated microlens array
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DOI：10.1016/j.sbsr.2025.100808.png)
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Abstract
En 中文
• Microlens Array integrated in SERS microfluidic chip boosts optical focusing and Raman signal collection efficiency. • Power density increased from 40 W/cm2 to 700 W/cm2, achieving a fivefold improvement in signal-to-noise ratio. • MLA enables simultaneous excitation and detection of multiple analytes, facilitating parallel Raman scattering collection. • Reduced sensitivity to misalignments in the x, y, and z axes enhances reliability and uniformity in signal detection. • Robust platform for point-of-care diagnostics, real-time analysis, and high-throughput sensing applications.
Keywords:
Surface-enhanced Raman spectroscopy
Microlens array
Microfluidic chip
Multiplexing
Point-of-care diagnostics
Improving SERS
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