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Encoding microcarriers: Present and future technologies

delete2002-06-01
delete316
PRE
AI
K
Kevin Braeckmans
D
De Smedt, SC
M
Marc Leblans
R
Rudi Pauwels
J
Joseph Demeester
DOI：10.1038/nrd817delete
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Abstract

Abstract

En 中文
In answer to the ever-increasing need to carry out many assays simultaneously in drug screening and drug discovery, several microcarrier-based multiplex technologies have arisen in the past few years. The compounds to be screened are attached to the surface of microcarriers, which can be mixed together in a vessel that contains the target analyte. Each microcarrier has to be encoded to know which compound is attached to its surface. In this article, the methods that have been developed for the encoding of microcarriers are reviewed and discussed.
Keywords:
HERPES-SIMPLEX-VIRUS
COMBINATORIAL CHEMISTRY
MULTIPLEXED ANALYSIS
CHEMICAL LIBRARIES
GENE-EXPRESSION
BEAD
CYTOKINES
TAGS
QUANTIFICATION
CLASSIFICATION
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Nature Reviews Drug Discovery cover
Nature Reviews Drug Discovery
IF:
101.8
Papers:
5.1K
Citations:
5.3W

Organization

No organization information available