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Endocuff Vision-enhanced colonoscopy: Does it improve polyp detection?
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DOI：10.3748/wjg.v32.i12.113927.png)
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Abstract
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BACKGROUND Screening by colonoscopy plays a pivotal role in the decreasing incidence and mortality rates associated with colorectal cancer. However, studies continue to highlight significant miss rates in standard colonoscopy. To address this challenge, an endoscopic-assisting device, Endocuff-Vision, aims to enhance mucosal inspection and improve polyp detection. Although many studies have discovered promising results with the Endocuff, other large studies report inconsistent findings. AIM To evaluate the real-world effectiveness and safety profile of the Endocuff. METHODS We conducted a non-randomized prospective trial by recruiting consenting and eligible participants aged 18+ years (n = 375) undergoing a colonoscopy at the Montfort Hospital (Ontario, Canada). The Endocuff Vision was used in all colonoscopies. Primary outcomes assessed the Endocuff's polyp detection rate compared to retrospective controls of standard colonoscopy dating up to 5 years. The control cohort (n = 375) was established by sample-matching. Secondary outcomes included safety and patient tolerance. RESULTS Colonoscopy with Endocuff in our study yielded a significantly lower overall polyp detection rate compared to controls (72.2% vs 88.7%, P < 0.01). The Endocuff device was well tolerated (94.7%), with no adverse events reported. CONCLUSION In this real-world study, Endocuff-enhanced colonoscopy was not superior to standard colonoscopy. Further larger scale studies with our population are required to validate findings.
Keywords:
Polyp detection
Colonoscopy
Screening
Endocuff
Endocuff-Vision
Colon cancer
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