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Engineering mammalian cells for solid-state sensor applications

delete2001-09-01
delete26
PRE
AI
F
F R Bloom
P
P. Buford Price
G
Guifang Lao
J
Jiu Lin Xia
J
John H. Crowe
B
Battista, JR
R
Richard F. Helm
S
Steve Slaughter
M
Malcolm Potts *
DOI：10.1016/S0956-5663(01)00175-0delete
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Abstract

Abstract

En 中文
A fundamental advance in the development and application of cell- and tissue-based biosensors would be the ability to achieve air-dry stabilization of mammalian (especially human) cells with subsequent recovery following rehydration. The would allow for the preparation of sensors with extended shelf lives, only requiring the addition of water for activation. By understanding and subsequently employing the tactics used by desiccation-tolerant extremophiles, it may be possible to design stabilized mammalian cell-based biosensors. The approaches required to realize this goal are discussed and illustrated with several examples. (C) 2001 Elsevier Science B.V. All rights reserved.
Keywords:
desiccation tolerance
cyanobacteria
sucrose
anhydrophile
hydrophilin
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Biosensors and Bioelectronics cover
Biosensors and Bioelectronics
IF:
10.5
Papers:
1.8W
Citations:
7.7W

Organization

No organization information available