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Enhanced Neuroprotective Effects of Remdesivir-Loaded Solid Lipid Nanoparticles in Ethanol-Induced Neurodegenerative Model: Role of TREM/PPARγ/NLRP3
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DOI：10.1016/j.alcohol.2026.04.006.png)
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Abstract
En 中文
• RDV-SLNs protected against ethanol-induced neurodegeneration. • Improved memory and cognition in NOR, MWM, and Y-Maze tests. • Reduced oxidative stress and restored antioxidant levels. • Increased PPAR-γ and suppressed NLRP3, TREM1, and TREM2.
Keywords:
Neuroprotection
Remdesivir-loaded solid lipid nanoparticles
Ethanol-induced neurodegeneration
PPAR-γ
NLRP3
Journal
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2.9
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192
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3.1K
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