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Enhancing the efficacy of ulcerative colitis treatment by inhibiting LCN2-mediated pyroptosis through traditional processing techniques: With the rhizome of Atractylodes macrocephala Koidz. as an example

delete2026-06-16
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PRE
AI
A
Anran Zhang
R
Rou Wen
H
Hailian Zheng
Z
Zhenqi Liu
J
Jingwen Wang
J
Jin Xue
H
Huan Yu *
C
Chao Li *
DOI:10.1016/j.jep.2026.122037delete
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Abstract

Abstract

En 中文
Atractylodes Macrocephala Rhizome (AMR), the dried rhizome of Atractylodes macrocephala Koidz (family Asteraceae), is a commonly used Chinese herbal medicine for treating ulcerative colitis (UC) and has extensive applications in both Traditional Chinese Medicine (TCM) and modern medicine. The therapeutic effects of its distinctive processed variety, rice-washed water processed Atractylodis Macrocephalae Rhizoma (Migan Shui Piao Baizhu, R-AMR), have yet to be reported, and its potential mechanisms of action require further exploration.

Journal

Journal of Ethnopharmacology cover
Journal of Ethnopharmacology
IF:
5.4
Papers:
2.6K
Citations:
6.2W

Organization

J
jiangxi university of chinese medicine
Scholars:
414
Papers: 116
Citations: 0
W
wenzhou medical university
Scholars:
6.2K
Papers: 1.6K
Citations: 0
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