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Epidermal deletion of Kindlin-1 drives matrix changes in the mouse skin and altered responses to ultraviolet radiation

delete2026-04-28
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OA
AI
G
Giovana Carrasco *
E
Emily R Webb
M
Molly R Danks
M
Morwenna Muir
D
David Hardman
C
Chinmayi Pednekar
R
Roza H A Masalmeh
M
Martin Lee
R
Rashi Krishna
A
Alex von Kriegsheim
M
Miguel O Bernabeu
A
Albena T Dinkova-Kostova
V
Valerie G Brunton
DOI:10.1016/j.jdermsci.2026.04.007delete
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Abstract

Abstract

En 中文
Kindler syndrome (KS) or Kindler epidermolysis bullosa (KEB) is a rare genetic autosomal skin fragility disorder with photosensitivity and abnormal pigmentation, with patients also having an increased risk of developing cutaneous squamous cell carcinoma (cSCC).
Keywords:
Kindler syndrome
Kindler epidermolysis bullosa
epithelial-to-mesenchymal transition
UV radiation
antioxidant
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Journal

Journal of Dermatological Science cover
Journal of Dermatological Science
IF:
4
Papers:
3.6K
Citations:
6.4K

Organization

U
University of Dundee
Scholars:
1.3W
Papers: 1.1W
Citations: 1.6W
U
University of Edinburgh
Scholars:
5.1W
Papers: 4.5W
Citations: 70
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