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ERα maintains the junctional function of testicular Sertoli cells by activating the PKR pathway via upregulation of c-Fos

delete2026-04-17
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PRE
AI
X
Xiaoyu Ma
Z
Zhaojun Yu
Y
Yanna Yang
Z
Zhili Yao
J
Jie Wu
Y
Yanfen Fang
J
Jianming Sun
J
Jianmin Mao
H
Haixia Zhao *
C
Changcheng Zhang *
DOI:10.1016/j.mce.2026.112808delete
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Abstract

Abstract

En 中文
• ERα is a key transcription factor maintaining Sertoli cell junctional function • ERα facilitates the transcription and translation of c-Fos • c-Fos is essential for activating the PKR pathway • PKR pathway indirectly regulates Sertoli cell junctional function
Keywords:
ERα
Sertoli cell
c-Fos
PKR pathway
junctional function

Journal

Molecular and Cellular Endocrinology cover
Molecular and Cellular Endocrinology
IF:
3.6
Papers:
8.0K
Citations:
1.6W

Organization

S
Shanghai University of Traditional Chinese Medicine
Scholars:
1.7K
Papers: 470
Citations: 1.3W
C
China Three Gorges University
Scholars:
1.2K
Papers: 382
Citations: 0
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