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Eryngium species in diabetes management: a systematic review of ethnopharmacological evidence and mechanisms of action
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DOI：10.1016/j.jep.2026.122049.png)
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Abstract
En 中文
• Eryngium species exhibit multi-target hypoglycemic effects involving glucose regulation, insulin signaling, and lipid metabolism pathways. • Most studies lack ethnopharmacological consistency, using non-traditional extracts and arbitrary dosages, limiting their translational relevance. • Future research should integrate traditional knowledge, standardized extracts, and mechanistic validation to improve clinical applicability. • E. cymosum, E. billardierei, and E. creticum show the greatest translational potential based on mechanistic and ethnopharmacological evidence.
Keywords:
Eryngium
Ethnopharmacology
Type 2 diabetes
Action mechanisms
Translational relevance
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5.4
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2.6K
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6.2W
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