Evidence for somatic mutation screening on aggressive prolactinomas

Marily Theodoropoulou

doi:10.1038/s41574-024-01010-x

Evidence for somatic mutation screening on aggressive prolactinomas

2024-06-17

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Marily Theodoropoulou *

DOI：10.1038/s41574-024-01010-x

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The recent Consensus Statement on the diagnosis and management of prolactin-secreting pituitary adenomas (prolactinomas) drew attention to molecular pathogenetic mechanisms. We comment that somatic screening for SF3B1 hotspot variants in select cases might alert to aggressive tumour behaviour and prompt the timely management and intense follow up of these challenging tumours.

Evidence for somatic mutation screening on aggressive prolactinomas

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