Expert consensus on endoscopic papillectomy using a Delphi process

doi:10.1016/j.gie.2021.04.009

Expert consensus on endoscopic papillectomy using a Delphi process

2021-10-01

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DOI：10.1016/j.gie.2021.04.009

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Background and Aims: Consensus regarding an optimal algorithm for endoscopic treatment of papillary adenomas has not been established. We aimed to assess the existing degree of consensus among international experts and develop further concordance by means of a Delphi process. Methods: Fifty-two international experts in the field of endoscopic papillectomy were invited to participate. Data were collected between August and December 2019 using an online survey platform. Three rounds were conducted. Consensus was defined as >= 70% agreement. Results: Sixteen experts (31%) completed the full process, and consensus was achieved on 47 of the final 79 statements (59%). Diagnostic workup should include at least an upper endoscopy using a duodenoscope (100%) and biopsy sampling (94%). There should be selected use of additional abdominal imaging (75%-81%). Patients with (suspected) papillary malignancy or over 1 cm intraductal extension should be referred for surgical resection (76%). To prevent pancreatitis, rectal nonsteroidal anti-inflammatory drugs should be administered before resection (82%) and a pancreatic stent should be placed (100%). A biliary stent is indicated in case of ongoing bleeding from the papillary region (76%) or concerns for a (micro)perforation after resection (88%). Follow-up should be started 3 to 6 months after initial papillectomy and repeated every 6 to 12 months for at least 5 years (75%). Conclusions: This is the first step in developing an international consensus-based algorithm for endoscopic management of papillary adenomas. Surprisingly, in many areas consensus could not be achieved. These aspects should be the focus of future studies.

Keywords:

LACTATED RINGERS SOLUTION

PANCREATIC STENT PLACEMENT

RETROGRADE CHOLANGIOPANCREATOGRAPHY

SNARE PAPILLECTOMY

AMPULLARY TUMORS

AGGRESSIVE HYDRATION

SUBMUCOSAL INJECTION

RECTAL NSAIDS

RISK

TRIAL

Expert consensus on endoscopic papillectomy using a Delphi process

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