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Export or explode: Export defects cause micronucleus membrane rupture
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DOI：10.1083/jcb.202603041.png)
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Abstract
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Micronucleus membrane rupture drives genome instability; however, the mechanisms governing this phenomenon remain unclear. Zych and colleagues reveal that impaired protein export, caused by reduced levels of the transport protein RCC1, drives micronucleus expansion, leading to nuclear envelope rupture.
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