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Factors Associated With Discordant Blood Pressure Measures among Very Old Adults: Results From the Atherosclerosis Risk in Communities (ARIC) Study

delete2026-04-01
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PRE
AI
G
Grobman, Benjamin
H
Hannah Col
K
Khan, Md Marufuzzaman
D
Dhrumil Patil
M
Mingyu Zhang
R
Ruth-Alma N. Turkson-Ocran
L
Long H Ngo
C
Cluett, Jennifer L.
M
Mukamal, Kenneth
E
Elizabeth Selvin
P
Pamela L. Lutsey
B
B. Gwen Windham
T
Thomas Mosley
L
Lynne Wagenknecht
T
Timothy Hughes
J
Josef Coresh
K
Kim Ring
A
Arielle Valint
S
Stephen P. Juraschek
DOI:10.1161/HYPERTENSIONAHA.125.26377delete
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Abstract

Abstract

En 中文
BACKGROUND:Home blood pressure (BP) monitoring (HBPM) is increasingly used as an alternative to office BP. However, factors influencing agreement between office and home BP among very old adults remain unclear.METHODS:During ARIC (Atherosclerosis Risk in Communities) visit 10, participants underwent 3 automated office BP (AOBP) measurements using an Omron HEM-907XL and performed HBPM twice daily for 8 days using an Omron BP7450. Discordance was defined as a systolic BP difference of +/- 10 mm Hg between mean AOBP and HBPM. Multivariable regression models evaluated demographic, anthropometric, and clinical factors associated with discordance.RESULTS:Among 792 participants (58% female; mean age, 84 +/- 3.7 years), mean systolic BP was 130.6 mm Hg (AOBP) and 129.6 mm Hg (HBPM). Despite a minimal average difference (1.0 +/- 15.7 mm Hg), 49% had >= 10 mm Hg systolic BP discordance. Higher AOBP was associated with greater discordance. Compared with females, males had lower AOBP relative to HBPM (-4.69 mm Hg [95% CI, -6.86 to -2.51]). Smaller arm circumference was associated with higher discordance (beta=14.4 mm Hg [95% CI, 4.78-24.04]). Frail adults had lower AOBP relative to HBPM (beta, -5.1 mm Hg [95% CI, -11.0 to 0.9]). Baseline AOBP systolic BP >= 140 mm Hg strongly predicted discordance >=+10 mm Hg (odds ratio, 8.27 [95% CI, 5.52-12.40]). Participants aged 91 to 100 years had lower AOBP than those aged 78 to 80 years (beta, -5.0 mm Hg [95% CI, -10.06 to 0.001]).CONCLUSIONS:Among very old adults, substantial BP discordance between AOBP and HBPM was common and influenced by higher BP, age, male sex, arm circumference, and frailty.
Keywords:
arm
blood pressure
cardiovascular disease
dementia

Journal

Hypertension cover
Hypertension
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8.2
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