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False-Positive 99mTc-Pyrophosphate Uptake Due to Myocardial Calcification from Prior Viral Myocarditis

delete2026-05-01
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PRE
AI
E
Eshghi, Anna
S
Stratford, Rylen
V
Vallurupalli, Srikanth
E
Eichhorn, Joshua *
DOI：10.1097/RLU.0000000000006355delete
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Abstract

Abstract

En 中文
A patient underwent 99mTc-pyrophosphate (PYP) imaging to evaluate for suspected cardiac amyloidosis. Planar imaging demonstrated diffusely increased radiotracer uptake throughout the left ventricular myocardium. On SPECT/CT, these regions of uptake corresponded to extensive myocardial calcifications. Patient had a history of severe myocarditis a year prior with extensive fibrosis documented by cardiac MRI. This case underscores the importance of SPECT/CT correlation in differentiating true cardiac amyloid deposition from false-positive PYP uptake due to dystrophic myocardial calcification.
Keywords:
cardiac amyloidosis
pyrophosphate scan
myocarditis

Journal

Clinical Nuclear Medicine cover
Clinical Nuclear Medicine
IF:
9.6
Papers:
1.1W
Citations:
6.9K

Organization

U
university of arkansas medical sciences
Scholars:
169
Papers: 113
Citations: 0
U
University of Arkansas System
Scholars:
1.8W
Papers: 1.5W
Citations: 295
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