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Fat-Induced Signal-oscillation Analysis Enhances Myocardial Iron Deposition Detection in Myocardial Infarction on Cardiac T2* Mapping

delete2026-06-29
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OA
AI
R
Rui Chen
Y
Yuelong Yang
X
Xinyi Wu
Z
Zhigang Wu
Y
Yongzhou Xu
W
Wei Luo
C
Caiying Mo
X
Xinyi Luo
L
Liqi Cao
H
Hui Liu *
J
Jiajun Xie *
DOI:10.1016/j.jocmr.2026.102771delete
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Abstract

Abstract

En 中文
Accurate detection of myocardial iron deposition is essential for diagnosis, risk stratification and therapeutic decision-making. The black-blood cardiac T2* mapping is the guideline-recommended technique for detecting myocardial iron deposition. However, mixtures of fat (MF) can confound the results, because MF also reduces T2* values. The present study proposes a method that reduces MF-related overestimation of iron deposition in cardiac T2* mapping.
Keywords:
MI
myocardial infarction
CMR
cardiac magnetic resonance imaging
MF
mixtures of fat
TE
echo times
HIC
hypointense core
ROI
regions of interests
χv2
χv2
χv2
χv2
Reduced Chi-squared
ROC
receiver operating characteristic curves
AUC
area under the ROC curves
PPV
positive predictive value
NPV
negative predictive value
Cardiac T2* mapping
Myocardial iron deposition
Mixtures of fat
Guideline method
Fat-induced signal-oscillation analysis

Journal

Journal of Cardiovascular Magnetic Resonance cover
Journal of Cardiovascular Magnetic Resonance
IF:
6.1
Papers:
2.3K
Citations:
6.9K

Organization

S
siemens shenzhen magnetic resonance ltd
Scholars:
4
Papers: 4
Citations: 0
S
Sun Yat-Sen University
Scholars:
7.9K
Papers: 2.1K
Citations: 0
P
philips healthcare
Scholars:
74
Papers: 61
Citations: 0
G
guangzhou first people's hospital
Scholars:
59
Papers: 31
Citations: 0
Cited Papers

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