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Fenton reaction-enhanced mild photothermal therapy for cancer suppression with a multifunctional platform
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DOI：10.1016/j.jphotobiol.2025.113250.png)
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Abstract
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• Successfully synthesized a new type of multifunctional nanoplatform FSC-IR NPs. • FSC-IR NPs integrated IR 825 and self-augmented Fenton molecule FSC. • FSC-IR NPs downregulated the acidity of tumor cells by inhibiting CA IX. • Acidosis and mild PTT enhanced ROS generation for improved CDT. • PTT coupled with CDT significantly increased tumor damage.
Keywords:
FSC-IR NPs
cancer therapy
photothermal therapy
chemodynamic therapy
tumor acidity
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