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Finally, a use for balloons: Extended automated endovascular support enhances closed-loop resuscitation in a porcine model of shock

delete2026-06-05
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PRE
AI
E
Elizabeth C. Wood
G
Gomez, Micaela K. MD
L
Lane, Magan R. BS
S
Saxena, Juhi MD
S
Sullivan, Thomas J. BS
L
Laingen, Bonnie E. MS
R
Reid, Garrett R. BS
A
Azar, Elizabeth A. BS
J
Johnson, Austin MD, PhD
A
Adams, Jason Y. MS, MD
N
Neff, Lucas P. MD
W
Williams, Timothy K. MD
W
Winston-Salem, North Carolina
DOI:10.1097/TA.0000000000005039delete
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Abstract

Abstract

En 中文
Endovascular Perfusion Augmentation for Critical Care (EPACC) is a method of dynamic aortic balloon catheter titration for precision hemodynamic support. EPACC has the potential to augment hemodynamics in conjunction with conventional resuscitation strategies. We previously described how even short periods of EPACC, along with an automated fluid and drug delivery system termed Precision Automated Critical Care Management (PACC-MAN) can reduce resuscitation requirements over the first few hours after severe ischemia-reperfusion injury (IRI). We sought to understand if an initial 180 minutes of EPACC+PACC-MAN can offset vasopressor requirements over 24 hours of critical care compared with PACC-MAN alone in an established IRI model.
Keywords:
Noncompressible torso hemorrhage
automated critical care
REBOA

Journal

Journal of Trauma and Acute Care Surgery cover
Journal of Trauma and Acute Care Surgery
IF:
3.7
Papers:
5.6K
Citations:
1.3W

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