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Fluorescent Gold Nanodots Based Sensor Array for Proteins Discrimination

delete2015-04-10
delete109
PRE
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袁智勤 cover
袁智勤 (Zhiqin Yuan)
Y
Yi Du
Y
Yu‐Ting Tseng
M
Meihua Peng
N
Na Cai
Y
Yan He *
H
Huan‐Tsung Chang
E
Edward S. Yeung
DOI：10.1021/ac5045302delete
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Abstract

Abstract

En 中文
A series of dual-ligand cofunctionalized fluorescent gold nanodots with similar fluorescence and diverse surface properties has been designed and synthesized to build a protein sensing array. Using this chemical nose/tongue strategy, fluorescence response patterns can be obtained on the array and identified via linear discriminant analysis (LDA). Eight proteins have been well distinguished at low concentration (A(280) = 0.005) based on this sensor array. The practicability of this sensor array was further validated by high accuracy (100%) examination of 48 unknown protein samples.
Keywords:
METAL NANOCLUSTERS
ESCHERICHIA-COLI
QUANTUM DOTS
NANOPARTICLES
DNA
IDENTIFICATION
NANOCRYSTALS
POLYMERS
LIGANDS
DISEASE
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Analytical Chemistry cover
Analytical Chemistry
IF:
6.7
Papers:
4.7W
Citations:
15.9W

Organization

N
National Taiwan University
Scholars:
4.7W
Papers: 4.2W
Citations: 3.6W
S
shenyang institute of applied ecology, cas
Scholars:
1.3K
Papers: 1.1K
Citations: 6
H
hunan university
Scholars:
4.5W
Papers: 3.3W
Citations: 70
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