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FNDC1-driven macrophage polarization promotes breast cancer cell invasion

delete2026-04-27
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PRE
AI
B
Bin Lian
H
Huihui Yang
Q
Qinghong Qin
S
Sen Lian
C
Changyuan Wei *
DOI：10.1016/j.imlet.2026.107179delete
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Abstract

Abstract

En 中文
• FNDC1 is highly expressed in breast cancer tissues and correlates with lymph node metastasis. • FNDC1-containing exosomes drive macrophage polarization toward the M2 phenotype. • FNDC1-induced M2 macrophages enhance breast cancer cell migration and invasion.
Keywords:
FNDC1
breast cancer
macrophage polarization
M2 phenotype
exosomes

Journal

Immunology Letters cover
Immunology Letters
IF:
2.8
Papers:
4.5K
Citations:
6.1K

Organization

G
Guangxi Zhuang Autonomous Region People’s Hospital
Scholars:
1
Papers: 1
Citations: 0
G
Guangxi Medical University
Scholars:
1.6W
Papers: 7.1K
Citations: 8.0K
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