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Fragmentation Analysis of the MYC Enhancer in Cell-Free DNA by qPCR for Early Detection of Hepatocellular Carcinoma

delete2026-06-19
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PRE
AI
Y
Yan Jiang
X
Xuchu Wang
Y
Yibei Dai
Y
Yu Pan
Y
Yue Cheng
D
Depeng Wang
T
Tao Chen *
DOI:10.1111/hepr.70222delete
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Abstract

Abstract

En 中文
The early detection of hepatocellular carcinoma (HCC) remains a significant challenge. This study aimed to develop a quantitative PCR (qPCR) assay to analyze the fragment size distribution of cfDNA at the enhancer region of the oncogene MYC, evaluate its potential ability as a diagnostic biomarker for HCC.
Keywords:
cell-free DNA
chromatin accessibility
hepatocellular carcinoma
MYC
quantitative PCR

Journal

Hepatology Research cover
Hepatology Research
IF:
3.4
Papers:
4.2K
Citations:
4.9K

Organization

Z
zhejiang chinese medical university
Scholars:
4.2K
Papers: 1.4K
Citations: 0
Z
Zhejiang Hospital
Scholars:
274
Papers: 136
Citations: 831
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