Fresh frozen plasma-first approach is independently associated with improved survival in severely injured patients undergoing massive transfusion

2026-06-11

PRE

Allyson M. Hynes

Westein, Riley J. MD

Turner, Tyler J. MD

Conrardy, Ryan D. MS

Yang, Kai PhD

Boyle, Kelly A. MD

Levin, Jeremy H. MD

de Moya, Marc A. MD, FACS

DOI：10.1097/TA.0000000000005093

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Despite evidence supporting high fresh frozen plasma (FFP)–to–packed red blood cell (PRBC) ratios, the optimal initial blood product in severe injury is unknown. We hypothesized that an FFP-first approach is associated with improved survival.

Keywords:

Coagulopathy

hemorrhagic

massive transfusion

shock

resuscitation

Fresh frozen plasma-first approach is independently associated with improved survival in severely injured patients undergoing massive transfusion

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